Kratom, Biak-Biak, and Icthang are 3 common names referring to the same herb that is scientifically known as Mitragyna speciose. Kratom has traditionally been used for many health issues, such as a cough, muscle aches, diarrhea, and opioid withdrawal symptoms.
Research shows Kratom to contain a substance known as Mitragynine, which makes Kratom have specific effects similar to those of opioids (narcotics). Therefore, Kratom is nowadays used as a stimulant to improve mood, and as a potent analgesic to relieve moderate pain
Up to the moment, Kratom is a supplement that can be legally purchased without a prescription. However, certain countries and even certain states in the U.S ban Kratom administration. Other common names of Kratom include: Ketum, Kratumum, Thang, Thom, Kakuam, and Kraton
How does Kratom work
Kratom contains 2 main ingredients, including Mitragynine and 7-HMG, which work as agonists of the μ-opioid receptors in the brain. That’s how Kratom supplements stimulate the body and produce the opioid-like effects, such as pain relieving.
It is worth mentioning that there are 2 different strains of Kratom, depending on the country of origin, which include red veins, white veins, and green veins. While the red vein has a more potent analgesic effect; the white and green veins tend to have higher stimulatory and mood-enhancing effects.
How long does Kratom stay in your system
How long Kratom stays in humans’ systems is not accurately determined, as there is no sufficient evidence about Kratom’s half-life. Generally, Kratom is likely to remain in your system for up to 9.8 days since the last time you administered it.
The reason is that the half-life of mitragynine, which is the main ingredient resulting from Kratom in the system, is around 23.24 hours (+/- 16.07 hours). Therefore, within a range of 7.7 hours to 39.31 hours post-administration, 50% of the administered dose of mitragynine will no longer be active in your system, and so on till the administered dose is entirely eliminated.
Furthermore, other factors can significantly affect the duration Kratom stays in your system. Those factors differ from a person to another, including:
- Your age
- your body mass
- whether you’re a light or a heavy Kratom consumer.
- The administered dose. For example, if you administer an overdose, Kratom is much likely to stay longer in your system.
- Your metabolic rate of drugs. That determines how quickly your system can get rid of the different substances contained in Kratom and their metabolites.
- body fats
The high lipophilicity of mitragynine results in a high tendency to be stored in the fatty tissues in the body. Thus, it prolongs the time Kratom stays in your system, especially in those with high-fat content. In contrast, those with low-fat content in their bodies are likely to get rid of Kratom’s substances within a shorter time.
Will Kratom show on a drug test
Kratom was not likely to be detected at all during drug testing; but, recently, certain tests have been developed so as to specifically test for the different substances contained in Kratom, such as mitragynine, speciociliatine, and paynantheine.
Importantly, Kratom is not likely to show on the commonly used drug tests such as the 5-panel-drug tests (SAMHSA-5).
Additionally, Kratom detection is much prone to be affected by the factors shown below, which can result in showing negative results, even in the specific tests.
- the type of the tests you are required to undergo
- the time the test is performed. Each test has a specific time frame to detect certain drugs. Therefore, what a certain test can detect at a certain moment; another test can’t.
- individual factors that differ from a person to another, as shown above.
How long is Kratom detectable
Urine and blood
Up to 10 days or longer post-administration, Kratom is likely detectable in the urine, depending on whether you have taken only one dose, or you’re frequently taking Kratom. In blood samples, Kratom is likely detectable within a shorter time, equating to 24 hours post-administration or slightly longer.
Hair, saliva and fingernails
Hair-based tests are not considered for Kratom testing. However, there is no sufficient information, in regards to whether Kratom will/or will not show on hair-based drug tests.
On the other side, although saliva based-tests can detect Kratom, they are rarely considered, as urine offers the best medium for Kratom detection within a long time-frame, compared to the very short time-frame of saliva-based tests.
Can any test show the presence of Kratom in the system
As mentioned above, the commonly used drug tests can’t show the presence of Kratom in the system, such as SAMHSA-5 However, there are certain tests specifically developed to detect Kratom, including:
- Blood analysis
- Hair-based tests, including Gas chromatography/mass spectrometry, ELISA (enzyme-linked immunosorbent assays)
- Saliva-based tests, such as high-performance liquid chromatography (HPLC)
How is Kratom stored in the body
After administration, Kratom is well absorbed from the gastrointestinal tract, rising in the blood till each substance reaches a peak level in the plasma, such as mitragynine that reaches its peak concertation within 1.26 hours.
Afterward, Kratom diffuses through the bloodstream to different body parts, and so on till it is stored in the fatty tissues, and passes the blood-brain barrier towards the central nervous system.
Up to 50 micrograms of mitragynine per blood liter and up to 300 micrograms per liter were noticed in individuals administering Kratom for recreational purposes, and in case of overdose administration, respectively.